tRNAscan-SE: Searching for tRNA genes in genomic sequences

By Patricia P. Chan, Todd M. Lowe. Methods in molecular biology, 2019

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Transfer RNAs are the largest, most complex non-coding RNA family, universal to all living organisms. tRNAscan-SE has been the de facto tool for predicting tRNA genes in whole genomes. The newly developed version 2.0 has incorporated advanced methodologies with improved probabilistic search software and a suite of new gene models, enabling better functional classification of predicted genes. This chapter describes the use of the UNIX command-driven and online web versions, illustrating different search modes and options.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a892c7cc2d6edc1d14cb948bcbbdfd747d4d874c