Platelet reactivity in patients and recurrent events post-stenting: results of the PREPARE POST-STENTING Study.

By P. Gurbel, K. Bliden, K. Guyer, Peter W. Cho, K. A. Zaman, R. Kreutz, A. Bassi, U. Tantry. Journal of the American College of Cardiology, 2005

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Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation. (2010, result): “However, the individual response to dual antiplatelet therapy is not uniform, and consistent findings across multiple investigations support the association between a lower degree of platelet inhibition, a high on-treatment platelet reactivity, and the occurrence of atherothrombotic events.(3-10) Th”
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. (2009, background): “Patients treated with clopidogrel who demonstrate higher ex vivo platelet reactivity are at increased risk of ischemic events.(9-12) Variation in platelet function in response to clopidogrel has been associated with lipophilic statins, calcium channel blockers, proton pump inhibitors, St John’s wort”