Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors

By Nada A. Al-Tassan, N. H. Chmiel, J. Maynard, N. Fleming, Alison L. Livingston, Geraint T. Williams, A. Hodges, D. R. Davies, S. David, J. Sampson and 1 more. Nature Genetics, 2002

1,331 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/a7d37685ff62c0743ec27905c0c55e469d2a0f4b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. D. Hanahan
2. R. Weinberg

In Molecular Biology

1. Tomas Lindahl
2. D. Barnes
3. D. Slade
4. M. Radman
5. D. Hanahan
6. R. Weinberg

In Pathology and Forensic Medicine

1. R. Weinberg
2. D. Hanahan

Citations in the corpus

• Association of MUTYH and colorectal cancer (2006, background): “MUTYH has been associated with multiple colorectal adenomas (Al-Tassan et al, 2002) and with colorectal adenocarcinomas (Croitoru et al, 2004; Farrington et al, 2005).”
• Repair and genetic consequences of endogenous DNA base damage in mammalian cells. (2004, background): “The role of the Escherichia coli mug protein in the removal of uracil and 3,N(4)ethenocytosine from DNA.”
• Oxidative Stress Resistance in Deinococcus radiodurans (2011, background): “coli MutY homolog) that is involved in the repair of the mutagenic consequence of oxidative DNA damage, strongly predispose humans to a rare hereditary form of colorectal cancer called familial adenomatous polyposis (FAP) (13).”
• Milestones of Lynch syndrome: 1895–2015 (2015, background): “MYH-associated polyposis (MAP) In 2002, Al-Tassan et al.(180) reported biallelic germline mutations of the mutY homologue (MYH) base”
• Colorectal cancer and genetic alterations in the Wnt pathway (2006, background): “It was something of a surprise when a recessive ‘version’ of FAP was identified in 2002 (Al-Tassan et al., 2002).”