Inference of human population history from individual whole-genome sequences.

By Heng Li, Richard Durbin. 2011

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In Genetics

Citations in the corpus

Stairway Plot 2: demographic history inference with folded SNP frequency spectra (2020, methodology): “In recent years, several methods have been developed to infer population size changes over time without the need for specifying parameters of the underlying population model [1 – 8], which are referred to as nonparametric or model-flexible methods.”
Insights into human genetic variation and population history from 929 diverse genomes (2019, background): “The distribution of coalescence times between chromosomes sampled from the same population can be used to infer changes in effective population size over time (20, 21), but resolution in recent times is limited when analysing single human genomes, and haplotype phasing errors can cause artefacts whe”
Efficient ancestry and mutation simulation with msprime 1.0 (2021, background): “…in population genetics use the distribution of coalescence rates be-tween pairs of lineages to infer effective population sizes over time (Li and Durbin 2011; Sheehan et al. 2013; Schiffels and Durbin 2014) or split times and subsequent migration rates between populations (Wang et al.…”
BEAST 2.5: An advanced software platform for Bayesian evolutionary analysis (2018, background): “For example, it has been shown that making use of this large-scale genomic structure can lead directly to powerful insights into ancestral population dynamics [96, 97].”
Visualizing spatial population structure with estimated effective migration surfaces (2014, background): “It is possible that the pairwise sequentially Markov coalescent [51], extended to deal with pairs of individuals [52], could also provide useful alternative distance matrices that could be visualized as an EEMS.”
Craniofacial Feminization, Social Tolerance, and the Origins of Behavioral Modernity (2014, background): “According to Li and Durbin (2011), effective population size in Africa started to increase 700,000–500,000 years ago to a peak 200,000–100,000 years ago; this growth was followed by a drop in effective population size, until it began to increase again 50,000–30,000 years ago.”