Janus kinase 3 (Jak3) is essential for common cytokine receptor γ chain (γc)-dependent signaling: comparative analysis of γc, Jak3, and γc and Jak3 double-deficient mice
By Kotaro Suzuki, H. Nakajima, Y. Saito, T. Saito, W. Leonard, I. Iwamoto. 2000
127 citations recorded by the source corpus.
Subfields: Immunology, Oncology
View Paper: https://www.semanticscholar.org/paper/a76334300308cf0b5c1507e7b17a402217bfe30d
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In Immunology
Citations in the corpus
- Natural Killer Cells: Development, Maturation, and Clinical Utilization (2018, background): “These receptors have no intrinsic kinase activity, so signal transduction in response to γc cytokines is initiated by receptor-associated Janus kinases (JAKs) which phosphorylate different STAT molecules in a cytokine-dependent manner (66, 67).”