Integration from proteins to organs: the Physiome Project
By Peter John Hunter, T. Borg. Nature reviews. Molecular cell biology, 2003
529 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/a735513f0d3b5d9beacebc5076329b2688f2c594
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Citations in the corpus
- OpenSim: Open-Source Software to Create and Analyze Dynamic Simulations of Movement (2007, background): “The Physiome Project [78] outlines this challenge and some of the important benefits of its success.”
- The principles of collective animal behaviour (2006, unknown): “Similar progress has been made in the study of other complex biological systems from human organs ( Hunter & Borg 2003 ) to ecosystems (Levin 2000).”
- Multiscale modeling meets machine learning: What can we learn? (2019, methodology): “…and multiscale modeling have emerged as a promising technologies to build organ models by systematically integrating knowledge from the molecular, cellular, and tissue levels [25, 43] as evidenced by initiatives like the United States Federal Interagency Modeling and Analysis Group IMAG [82, 136].”
- CellML: its future, present and past. (2004, background): “Over the past 20 years, the biological sciences have experienced an ‘‘information explosion’’ (Loew and Schaff, 2001; Hunter and Borg, 2003).”
- Systems biology in drug discovery (2004, background): “1 ), such efforts are currently limited to simple organisms or to specific minimal pathways (and generally in very specific cell and environmental contexts) in higher organism”
- Phenomics: the next challenge (2010, background): “Such models would ideally span the life cycle of organisms, from instantaneous regulatory changes to generation-length phenomena such as development and ageing (spanning 15 orders of magnitude), and explain the behaviour of biological systems from the molecular to the whole-organism level (spanning ”