Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes.

By K. Alexander, Anita Y. Chen, M. Roe, L. Newby, C. Gibson, Nancy M. Allen-LaPointe, C. Pollack, W. Gibler, E. Ohman, E. Peterson. Journal of the American Medical Association (JAMA), 2005

685 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Surgery

View Paper: https://www.semanticscholar.org/paper/a6bac76530b27763ae497b9d16233bb70699a3c5

How researchers see this paper

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In Cardiology and Cardiovascular Medicine

1. Allan S. Jaffe
2. Rick A. Nishimura
3. J. Halperin
4. Hani Jneid
5. Gerhard Hindricks
6. M. Creager
7. C. Yancy

In Surgery

1. M. Creager

Citations in the corpus

• 2007 focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice guidelines. (2008, background): “In a large community-based egistry study, 42% of patients with UA/NSTEMI received xcessive initial dosing of at least 1 antiplatelet or antihrombin agent (unfractionated heparin [UFH], LMWH, r GP IIb/IIIa inhibitor) (73).”
• 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. (2017, background): “ACS patients with chronic kidney disease (CKD) receive frequently excess dosing with antithrombotics, contributing to the increased bleeding risk.(275) Consequently, in patients with known or anticipated reduction of renal function, several antithrombotic agents should either be withheld or their do”
• ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. (2012, neutral): “In addition, observational studies have shown frequent overdosing of antithrombotic therapies.(190) It is therefore key to maintain a high index of suspicion for myocardial infarction in elderly patients who present with atypical complaints and to pay specific attention to proper dosing of antithrom”