A universal RNAi-based logic evaluator that operates in mammalian cells

By Keller Rinaudo, L. Bleris, Rohan Maddamsetti, Sairam Subramanian, Ron Weiss, Yaakov Benenson. Nature Biotechnology, 2007

473 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a6ade69249f02aa630ea200c30a77b298f5ec2dd

How researchers see this paper

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In Molecular Biology

1. Yaakov Benenson
2. Itamar Willner
3. Christopher A. Voigt
4. Alvin Tamsir

Citations in the corpus

• Biomolecular computing systems: principles, progress and potential (2012, background): “Trans -acting RNA switches include small RNAs (sRNAs) in bacteria and microRNAs (miRNAs) in higher eukaryotes. miRNAs have been extensively studied as the basis for complex logic in mammalian cells, because multiple miRNAs that control the same gene implement NOR logic 74 .”
• Robust multicellular computing using genetically encoded NOR gates and chemical ‘wires’ (2010, background): “The dominant contribution to the dynamic range of the complete circuit is due to the intrinsic range of the final circuit (Supplementary Figure 7).”
• DNA computing circuits using libraries of DNAzyme subunits. (2010, background): “I' J' Q F2 (19) (20) (21) (4) (3) (22) (15) (16)”