Macrophages as regulators of tumour immunity and immunotherapy

By D. DeNardo, B. Ruffell. Nature reviews. Immunology, 2019

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Tumor-Associated Macrophages in Tumor Immunity (2020, background): “TAMs can promote tumor growth, invasion, metastasis, and drug resistance (5).”
Macrophages in immunoregulation and therapeutics (2023, methodology): “Macrophage targeting is now being studied because of the growing importance of cancer immunotherapy.(282) High mobility group box 1 (HMGB1), heat shock proteins (HSPs), and ATP are examples of DAMPs that are released when cells die in tumors.”
Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity (2021, background): “Hence, number efforts have been made to expand M1-type macrophages and reset M2 macrophages reprogramming or polarization at tumor sites for achieving the anti-tumor effect via leveraging on material engineering.(56) Previously, researchers constructed PEGDA and thiolated gelatin poly(ethylene glyco”