FcϵRI as a paradigm for a lipid raft-dependent receptor in hematopoietic cells

By D. Holowka, B. Baird. 2001

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Investigation of Early Events in FcεRI-Mediated Signaling Using a Detailed Mathematical Model1 (2003, background): “An alternative model to ours for the initiation of Fc RI signaling is based on the observation that receptor monomers are found primarily outside of lipid rafts, while aggregated receptors and Lyn tend to colocalize within rafts (71).”