Advances in Radiation Therapy: Conventional to 3D, to IMRT, to 4D, and Beyond

By M. Bucci, A. Bevan, M. Roach. Ca, 2005

363 citations recorded by the source corpus.

Modern advances in computers have fueled parallel advances in imaging technologies. The improvements in imaging have in turn allowed a higher level of complexity to be incorporated into radiotherapy treatment planning systems. As a result of these changes, the delivery of radiotherapy evolved from therapy designed based primarily on plain (two dimensional) x‐ray images and hand calculations to three‐dimensional x‐ray based images incorporating increasingly complex computer algorithms. More recently, biologic variables based on differences between tumor metabolism, tumor antigens, and normal tissues have been incorporated into the treatment process. In addition, greater awareness of the challenges to the accuracy of the treatment planning process, such as problems with set‐error and organ movement, have begun to be systematically addressed, ushering in an era of so‐called Four‐Dimensional Radiotherapy. This review article discusses how these advances have changed the way the most common neoplasms are treated now and will be treated in the near future.

Subfields: Radiation, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/a610e7fa2ea5d36347e723e785a72f0bfbd54f65

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In Radiation

1. W. Galster
2. K. Ledingham

Citations in the corpus

• Laser-driven particle and photon beams and some applications (2010, background): “Recent advances in radiation therapy have resulted in intensity-modulated particle therapy (IMPT), which is similar in principle to intensity-modulated radiation therapy (IMRT) using x-rays (Bucci et al 2005).”