Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal.

By Yue Wang, Zhenyu Xu, Junfeng Jiang, Chen Xu, Jiuhong Kang, Lei Xiao, Minjuan Wu, J. Xiong, Xiaocan Guo, Hou-qi Liu. Developmental Cell, 2013

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Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA (2017, background): “Examples of this type of interaction include the intergenic lincRNA-ROR, which inhibits miR-145 in pluripotent embryonic stem cells (ESCs) [44].”
Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer (2014, background): “Notably, lncRNA HULC is highly upregulated in liver cancer and plays an important role in tumorigenesis [7].”
Long Non-coding RNAs in the Cytoplasm (2016, background): “Interaction between linc-RoR and miR-145 prevents mRNA of some important transcription factors (TFs) like Oct4, sox2, and Nanog in human embryonic stem cells (hESCs) from miRNA-mediated regulation [68,69].”
Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches. (2016, background): “Therefore, linc-RoR may prevent the miRNA-mediated suppression of these transcription factors and maintain the self-renewing potential of embryonic stem cells (284).”
Noncoding RNA:RNA Regulatory Networks in Cancer (2018, background): “Linc-ROR was first identified as a lncRNA that regulates the reprogramming of pluripotent stem cells, which could partly be due to its miRNA sponging effect that regulates stem cell factors OCT4 (POU class 5 homeobox 1), NANOG (Nanog homeobox) and SOX2 (SRY-box 2) [69,70].”