Amygdala hyperreactivity in borderline personality disorder: implications for emotional dysregulation.

By N. Donegan, C. Sanislow, H. Blumberg, R. Fulbright, Cheryl Lacadie, Pawel Skudlarski, John C. Gore, Ingrid R. Olson, Thomas H. McGlashan, B. Wexler. Biological Psychiatry, 2003

651 citations recorded by the source corpus.

Subfields: Applied Psychology, Clinical Psychology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/a5badf6f41de4020f2a17dbb161a1640935be94c

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Citations in the corpus

Emotion and evolving treatments for adult psychopathology. (2007, background): “Similarly, individuals with a history of trauma (e.g., Pollak & Sinha, 2002) and borderline personality disorder (e.g., Donnegan et al., 2003) have been shown to misidentify neutral facial features as threatening or angry.”
Oxytocin, vasopressin, and human social behavior. (2009, background): “Hypervigilance to emotionally laden social stimuli is further confirmed by studies showing enhanced amygdala reactivity to negative scenes [73] and to negative facial expressions [114], and even to neutral faces [46].”
The brain basis of emotion: A meta-analytic review (2012, background): “There is evidence of left amygdala hypoactivation in Asperger Syndrome (AS: Ashwin et al. 2007) and hyperactivation in Borderline Personality Disorder (BPD: Donegan et al. 2003; Koenigsberg et al. 2009).”
Affective Disturbance and Psychopathology: An Emotion Regulation Perspective (2013, background): “…inflexible, and dichotomous thinking (Wenzel, Chapman, Newman, Beck, & Brown, 2006), which may contribute to the primarily-negative experiences that are readily recalled to memory rather than more neutral or positive ones in BPD (Donegan et al., 2003; Korfine & Hooley, 2000; Kurtz & Morey, 1998).”
Toward a Model for Assessing Level of Personality Functioning in DSM–5, Part I: A Review of Theory and Methods (2011, background): “Likewise, patients with borderline personality disorder (BPD) are significantly more likely to assign negative attributes and emotions to the picture of a face with a neutral expression (Donegan et al., 2003; Wagner & Linehan, 1999).”
Amygdala-frontal connectivity during emotion regulation. (2007, background): “…in press) and personality disorders (McCloskey et al., 2005; New et al., 2007); furthermore, these patients also exhibit exaggerated amygdala reactivity to emotionally negative stimuli (Coccaro et al., in press; Rauch et al., 2000; Herpertz et al., 2001; Sheline et al., 2001; Donegan et al., 2003).”
The NimStim set of facial expressions: judgments from untrained research participants. (2009, neutral): “However, there is evidence to suggest that neutral faces may not always be perceived as emotionally neutral (Donegan et al., 2003; Somerville et al., 2004; Iidaka et al., 2005), especially for children (Thomas et al.”
Dialectical behaviour therapy: An increasing evidence base (2007, background): “It has been suggested that prefrontal and temporolimbic dysfunction may underlie the behavioural dyscontrol, affect dysregulation and social cognitive deficits that characterise BPD (Donegan et al., 2003; Paris, 2000; Silk, 2000).”
Guideline Watch: Practice Guideline for the Treatment of Patients With Borderline Personality Disorder (2005, background): “Limbic studies have found reduced volume in the amygdala and hippocampus (47, 48), altered amygdala activation (49, 50), and hippocampal hypometabolism (51).”
Hypermentalizing in Borderline Personality Disorder: A Model and Data (2015, background): “In line with this hypervigilance to social stimuli associated with BPD, neurobiological studies have demonstrated enhanced amygdala response coupled with regulatory deficits of the orbital and prefrontal cortices with the presentation of emotional stimuli (Domes et al., 2009; Frick et al., 2012; Don”