The mechanisms of action of gabapentin and pregabalin.
By G. Sills. Current opinion in pharmacology (Print), 2006
644 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Pediatrics, Perinatology and Child Health, Psychiatry and Mental health
View Paper: https://www.semanticscholar.org/paper/a4cf4f264d048f0f638d2ab6e07d5443ab41d924
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In Cellular and Molecular Neuroscience
In Pediatrics, Perinatology and Child Health
In Psychiatry and Mental health
Citations in the corpus
- A Comparison of the Pharmacokinetics and Pharmacodynamics of Pregabalin and Gabapentin (2010, positive): “Both are chemical analogues of gaminobutyric acid (GABA); however, neither drug has activity in GABAergic neuronal systems.([6-8]) Functionally, they are similar to the essential, metabolizable, branched-chain amino acid, leucine, with regard to competitive binding to a2d subunit types 1 and 2([9]) ”