Role of miRNAs and siRNAs in biotic and abiotic stress responses of plants

By Basel Khraiwesh, Jian‐Kang Zhu. Biochimica et Biophysica Acta, 2011

1,013 citations recorded by the source corpus.

Small, non-coding RNAs are a distinct class of regulatory RNAs in plants and animals that control a variety of biological processes. In plants, several classes of small RNAs with specific sizes and dedicated functions have evolved through a series of pathways. The major classes of small RNAs include microRNAs (miRNAs) and small interfering RNAs (siRNAs), which differ in their biogenesis. miRNAs control the expression of cognate target genes by binding to reverse complementary sequences, resulting in cleavage or translational inhibition of the target RNAs. siRNAs have a similar structure, function, and biogenesis as miRNAs but are derived from long double-stranded RNAs and can often direct DNA methylation at target sequences. Besides their roles in growth and development and maintenance of genome integrity, small RNAs are also important components in plant stress responses. One way in which plants respond to environmental stress is by modifying their gene expression through the activity of small RNAs. Thus, understanding how small RNAs regulate gene expression will enable researchers to explore the role of small RNAs in biotic and abiotic stress responses. This review focuses on the regulatory roles of plant small RNAs in the adaptive response to stresses.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/a4ccd6b771eebfa5a76ac7c089a5472e733c28cf

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. K. Scharf
2. M. B. Bitonti
3. Maria Greco
4. Ingo Ebersberger
5. Thomas Berberich
6. T. Gerats
7. L. Nover
8. C. Jonak

In Plant Science

1. Ye-Cheng Wang
2. K. Scharf
3. M. B. Bitonti
4. Shuai Gao
5. J. Song
6. Y. Zhang
7. B. Li
8. Maria Greco

Citations in the corpus

• Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, positive): “Recent studies have demonstrated that heavy metal-regulated gene expression can be also achieved at post-transcriptional levels by a group of microRNAs (Zhou et al., 2008, 2012; Huang et al., 2009, 2010; Lima et al., 2011; Wang et al., 2011; Chen et al., 2012; Khraiwesh et al., 2012).”
• miR394 and its target gene LCR are involved in cold stress response in Arabidopsis (2016, positive): “These stress-responsive miRNAs represent a newly found mechanism for plant adaptation to abiotic stresses (Phillips et al., 2007; Khraiwesh et al., 2012; Zhou et al., 2012a, 2012b; Yang and Chen, 2013).”
• The plant heat stress transcription factor (Hsf) family: structure, function and evolution. (2012, background): “Many other transcription factors [101, 145, 158–160], stress-induced proteins and metabolites, small non-coding RNAs as well as stress hormones such as ethylene (ETH), ABA, salicylic acid (SA) and jasmonic acid (JA) are integral parts of the highly complex response of plants as whole organisms in a ”
• Plant tolerance to high temperature in a changing environment: scientific fundamentals and production of heat stress-tolerant crops (2013, background): “Recently, it was, however, shown that an Arabidopsis mitochondrial transcription termination-factor related protein enhances thermotolerance in the absence of HSP101, via mitochondrial oxidative damage control (Kim et al., 2012).”
• Reconsidering plant memory: Intersections between stress recovery, RNA turnover, and epigenetics (2016, background): “Chromatin and small interfering RNA (siRNA) abundance also change in response to environmental conditions (76, 77).”
• Genomics of Cold Hardiness in Woody Plants (2014, background): “The stress response of plants also involves small RNAs; the reader is referred to a recent review for more information (Khraiwesh et al., 2012).”
• Drought, salt, and temperature stress-induced metabolic rearrangements and regulatory networks (2012, positive): “At the molecular level, gene expression is modified upon stress (Chinnusamy et al., 2007; Shinozaki and Yamaguchi-Shinozaki, 2007) and epigenetic regulation plays an important role in the regulation of gene expression in response to environmental stress (Hauser et al., 2011; Khraiwesh et al., 2011).”