The Effectiveness and Risks of Long-Term Opioid Therapy for Chronic Pain: A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop

By R. Chou, Judith Axler Turner, E. Devine, R. Hansen, S. Sullivan, I. Blazina, T. Dana, C. Bougatsos, R. Deyo. Annals of Internal Medicine, 2015

1,425 citations recorded by the source corpus.

Subfields: Anesthesiology and Pain Medicine, Pharmacology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/a4ca476774a0efa8254600e1d9acc4cc21f71e1f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Anesthesiology and Pain Medicine

1. D. Dowell
2. Tamara M. Haegerich
3. Anne Case
4. R. Chou
5. Angus Deaton

In Pharmacology

1. R. Chou
2. Nora D. Volkow
3. K. Kroenke
4. Tamara M. Haegerich
5. D. Dowell
6. B. Löwe
7. R. Spitzer
8. Janet B W Williams

In Public Health, Environmental and Occupational Health

1. D. Dowell
2. Tamara M. Haegerich
3. Anne Case
4. K. Kroenke
5. Angus Deaton

Citations in the corpus

• Rising morbidity and mortality in midlife among white non-Hispanic Americans in the 21st century (2015, background): “Pain prevalence might have been even higher without the drugs, although long-term opioid use may exacerbate pain for some (26), and consensus on the effectiveness and risks of long-term opioid use has been hampered by lack of research evidence (27).”
• Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis (2016, background): “Systematic review Introduction Chronic pain, often defined as pain lasting longer than 3 months or past the normal time for tissue healing [1], can lead to significant medical, social, and economic consequences, relationship issues, lost productivity, and larger health care costs.”
• Opioid Abuse in Chronic Pain--Misconceptions and Mitigation Strategies. (2016, background): “Opioid doses of more than 100 MME91,92 are disproportionately associated with overdose-related hospital Several mitigation strategies for risk assessment of opioid misuse have been proposed.(74) These include the following:”
• CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016 (2016, methodology): “A previously published systematic review sponsored by the Agency for Healthcare Research and Quality (AHRQ) on the effectiveness and risks of long-term opioid treatment of chronic pain (10,40)”
• Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial (2018, background): “(%) Significant PMP finding at any visith 6 (5) 4 (3) 2 (−3 to 7) .”
• CDC guideline for prescribing opioids for chronic pain (2016, methodology): “Additional details on findings from the original review are available in the full 2014 AHRQ report (10, 32).”