Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology.

By P. Moreira, C. Carvalho, Xiongwei Zhu, Mark A. Smith, George Perry. Biochimica et Biophysica Acta, 2010

709 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/a43210111b1469ff68f3ba7bae3ca3b37ccce6c3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Physiology

1. Huaxi Xu

Citations in the corpus

• Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease (2020, background): “Aβ peptides can induce ROS production from mitochondria, leading to release of cytochrome c and apoptosis-inducing factor, thereby driving mitochondrial dysfunction, cell apoptosis and neuronal loss [97, 100].”