Nanoparticles in cancer therapy and diagnosis.

By I. Brigger, C. Dubernet, P. Couvreur. Advanced Drug Delivery Reviews, 2002

3,271 citations recorded by the source corpus.

Subfields: Biomaterials, Biomedical Engineering, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a3e1f5a9d397d95ed678e49b477d7e99ddd2f23d

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Citations in the corpus

Nanoparticle-based targeted drug delivery (2009, background): “Hence, hydrophobicity influences the in vivo fate of nanoparticles (Brigger et al., 2002; Muller et al., 1996).”
A review of current nanoparticle and targeting moieties for the delivery of cancer therapeutics (2012, positive): “However, there remain significant barriers to transport that often result in insufficient drug concentrations at the tumor site and, consequently, little therapeutic efficacy (Brigger et al., 2002; Gu et al., 2007).”
Paclitaxel-loaded PEGylated PLGA-based nanoparticles: in vitro and in vivo evaluation. (2009, background): “The rationale behind this approach is to increase antitumor efficacy while reducing systemic side effects [11].”
Does the Antibacterial Activity of Silver Nanoparticles Depend on the Shape of the Nanoparticle? A Study of the Gram-Negative Bacterium Escherichia coli (2007, background): “Nanophasic and nanostructured materials are attracting a great deal of attention because of their potential for achieving specific processes and selectivity, especially in biological and pharmaceutical applications (5, 39).”
Magnetic nanoparticles in MR imaging and drug delivery. (2008, background): “However, the delivery of genes and their resulting transfection efficiencies are often limited by their short half-life in vivo, lack of specificity, and poor diffusion across cell membranes [193,194].”
Nanocarriers as an emerging platform for cancer therapy. (2007, background): “For example, upon intravenous injection, particles are rapidly cleared from the bloodstream by the reticuloendothelial defence mechanism, regardless of particle compositio”
Effect of Zeta Potential on the Properties of Nano-Drug Delivery Systems - A Review (Part 2) (2013, background): “Direct access to intravenously administered agent, rapid proliferated of endothelial cells and over expression of negatively charged functional groups along vessels are potentially exploitable feature of tumors [51-52].”
Porous silicon in drug delivery devices and materials. (2008, background): “Providing a controlled and localized release of therapeutics within the body are key objectives for increasing efficacy and reducing the risks of potential side effects [115–119].”