Synaptotagmin I functions as a calcium regulator of release probability

By R. Fernández-Chacón, A. Königstorfer, S. Gerber, Jesus M. Garcia, M. Matos, C. Stevens, N. Brose, J. Rizo, Christian Rosenmund, T. Sūdhof. Nature, 2001

967 citations recorded by the source corpus.

Subfields: Cell Biology, Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a3a734bf3d43e3b11f1745c2e3381fc079766746

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. W. Hong
2. T. Sūdhof
3. S. Harrison

In Cellular and Molecular Neuroscience

1. T. Sūdhof
2. J. Lipton
3. Mustafa Sahin

In Molecular Biology

1. W. Hong
2. T. Sūdhof
3. S. Harrison

Citations in the corpus

• Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle (2013, background): “Experiments with knockin mice, however, proved that Ca binding to Syt1 triggers neurotransmitter release (Fernández-Chacón et al., 2001; Sørensen et al., 2003; Pang et al., 2006a).”
• SNAREs and traffic. (2005, background): “Subsequent studies using the genetic approach in mice [111] and biochemical reconstitution in vitro [115] establish that synaptotagmin I is a Ca-sensor that couples action potential to fast exocytosis, a function dependent on its Ca-regulated interaction with phospholipids, PtdIns4,5P2, and the tran”