Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease

By T. T. Hove, C. Montfrans, M. Peppelenbosch, S. Deventer. Gut, 2002

602 citations recorded by the source corpus.

Subfields: Genetics, Hepatology, Immunology

View Paper: https://www.semanticscholar.org/paper/a2dfa869f2c466d817d311a25acd042399bbec4c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. C. A. Dinarello

In Immunology

1. C. A. Dinarello
2. A. Mantovani
3. C. Garlanda
4. M. Keel
5. O. Trentz

Citations in the corpus

• Granulomatous infectious diseases associated with tumor necrosis factor antagonists. (2004, background): “In vivo, infliximab has been shown to induce apoptosis of monocytes and T cells [26, 27].”
• Tumor necrosis factor antagonist mechanisms of action: a comprehensive review. (2008, methodology): “A study of 10 patients with Crohn's disease used TUNEL staining of lamina propria biopsy samples taken before and 24 h after treatment with infliximab at 5 mg/kg (ten Hove et al., 2002).”
• Interleukin-18 and IL-18 Binding Protein (2013, background): “The induction of fever, a well-studied property of IL-1α and IL-1β as well as acute phase proteins, TNFα and IL-6, is not a significant property of IL-18.”