Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts
By W. Zimmermann, Ivan Melnychenko, G. Wasmeier, M. Didié, H. Naito, U. Nixdorff, A. Hess, L. Budinsky, K. Brune, Bjela Michaelis and 4 more. Nature Medicine, 2006
1,004 citations recorded by the source corpus.
Subfields: Biomaterials, Genetics, Surgery
View Paper: https://www.semanticscholar.org/paper/a2be7ba4e28d394f379bc20074a227c305669e7a
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Citations in the corpus
- Nanowired three dimensional cardiac patches (2011, methodology): “(1 mg ml(21)) with the alginate solution followed by rapid mixing; (3) crosslinking of the alginate/nanowire solution by adding the bivalent crosslinker (for example, calcium gluconate); (4) freezing the crosslinked alginate in a homogeneous, cold (–20 8C) environment; and (5) lyophilization to prod”
- 3D printed complex tissue construct using stem cell-laden decellularized extracellular matrix bioinks for cardiac repair. (2017, background): “All rats received immunosuppressants as previously repo rted mixing rate (mg/kg body weight/d: azathioprine, 2; cyclosporine A, 5; methylprednisol one, 5) [12].”
- Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury. (2013, neutral): “Pre-clinical studies show a great potential for engineered heart tissue for replacement therapy (Naito et al., 2006; Zimmermann et al., 2006) while stem cell injections may be promising in the treatment of patients with acute MI (Martin-Rendon et al., 2008).”