Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial.

By R. Pauwels, S. Pedersen, W. Busse, W. Tan, Yu-zhi Chen, S. Ohlsson, A. Ullman, C. Lamm, P. O'Byrne. The Lancet, 2003

715 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

External validity of randomised controlled trials in asthma: to whom do the results of the trials apply? (2006, neutral): “7 There were 215 individual references in the relevant chapter of the GINA guidelines from which 17 qualifying RCTs were identified and included in the analysis (Figure 2).(13-29) The characteristics of the included RCTs are given in Table 2.”
Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma (2007, neutral): “The START study (Pauwels et al. 2003) enrolled 7,241 subjects, 5–66 years of age, who had mild asthma of less than 2 years’ duration, according to each subject’s report.”
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. (2009, background): “Although severe exacerbations are more common with poorly controlled asthma (52), they also occur in patients with otherwise mild (27) or well-controlled asthma (60).”