LigPlot+: Multiple Ligand-Protein Interaction Diagrams for Drug Discovery

By Roman A. Laskowski, M. Swindells. 2011

5,898 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Molecular Biology, Pharmacology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Computational Theory and Mathematics

1. David B. Ascher
2. Cristian Rocha-Roa
3. M. Guerrero
4. Jens Meiler
5. Gilles Pieffet
6. Tom L. Blundell
7. N. Arenas
8. M. Schroeder

In Molecular Biology

1. David B. Ascher
2. Brian Joseph Bender
3. Bernardo Ochoa-Montaño
4. Jens Meiler
5. Tom L. Blundell
6. Cristian Rocha-Roa
7. Ren Sun
8. M. Guerrero

In Pharmacology

1. Cristian Rocha-Roa
2. M. Guerrero
3. Jens Meiler
4. Gilles Pieffet
5. N. Arenas
6. Abdo A. Elfiky

Citations in the corpus

• Arpeggio: A Web Server for Calculating and Visualising Interatomic Interactions in Protein Structures (2017, methodology): “Some tools are available that aid in this understanding, such as the Ligand Protein Contacts server [10] and GIANT [9], and specific programs for ight © 2016 Published by Elsevier Ltd. rg/licenses/by/4.0/). calculating individual interaction types such as polar contacts in PyMOL and hydrogen bonds w”
• PLIP 2021: expanding the scope of the protein–ligand interaction profiler to DNA and RNA (2021, background): “There are a number of tools (29–37) analysing ligand–target interactions, but apart from one, they have a different focus and therefore suffer from some limitations: (29–33) detect only a limited set of interaction types and do not offer 3D visualisation, (34) requires extensive preparation of…”
• Design of a specific peptide against phenolic glycolipid-1 from Mycobacterium leprae and its implications in leprosy bacilli entry (2022, methodology): “Peptide oligomer interactions and homodimer/PGL-1 interactions were assessed with Ligplot+ software.(38)”
• Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality (2015, methodology): “The interaction between PA of the influenza B virus and the first five nucleotide in the RNA molecule is plotted in a two-dimensional diagram using LigPlot[95].”
• Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor (2018, methodology): “IP accumulation assays of WT Y1R for NPY/NPY analogues NPY Ac-NPY [A1]NPY [A2]NPY [A1,A2]NPY NPY(3-36) NPY(13-36)”