Predictability of the toxicity of multiple chemical mixtures to Vibrio fischeri: Mixtures composed of similarly acting chemicals

By R. Altenburger, T. Backhaus, W. Boedeker, M. Faust, M. Scholze, L. Grimme. 2000

416 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Health, Toxicology and Mutagenesis, Pollution

View Paper: https://www.semanticscholar.org/paper/a1c7ec0ce828284664428212085acca129c0dca7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Computational Theory and Mathematics

1. M. Cleuvers
2. N. Cedergreen

In Health, Toxicology and Mutagenesis

1. M. Cleuvers
2. D. Spurgeon
3. N. Cedergreen
4. E. Lahive
5. J. Meador

In Pollution

1. M. Cleuvers
2. D. Spurgeon
3. N. Cedergreen
4. E. Lahive
5. J. Meador

Citations in the corpus

• Quantifying Synergy: A Systematic Review of Mixture Toxicity Studies within Environmental Toxicology (2014, background): “This makes them ideal candidates for testing mixture models based on chemical mode of action and understanding the physiological mechanisms behind possible interactions [8,9].”
• Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid. (2004, methodology): “In the present study, the concept of concentration addition (Altenburger et al., 2000; Faust et al., 2001) was applied.”
• Rationale and Procedures for Using the Tissue-Residue Approach for Toxicity Assessment and Determination of Tissue, Water, and Sediment Quality Guidelines for Aquatic Organisms (2006, background): “These data are also supported by the results of Altenburger et al. (2000) who demonstrated dose additivity for a mixture of 16 phenol-type uncouplers.”
• Species Sensitivity to Toxic Substances: Evolution, Ecology and Applications (2020, background): “Thus, species that actively assimilated Cl via gills, such as the channel catfish (Ictalurus punctatus), showed greater sensitive to NO2 than species such as killifish (Fundulus heteroclitus), European eel (Anguilla anguilla) and bluegill (Lepomis macrochirus) that access Cl also through other (e.g.”
• Mechanistic studies on baseline toxicity and uncoupling of organic compounds as a basis for modeling effective membrane concentrations in aquatic organisms (2002, background): “Classification is a prerequisite for choosing the appropriate predictive Quantitative Structure-Activity Relationship (QSAR) (Hermens, 1989) and for characterization effects in mixtures (Altenburger et al., 2000).”