Amyloid Deposition, Hypometabolism, and Longitudinal Cognitive Decline

By Susan M. Landau, Mark A. Mintun, A. Joshi, Robert A. Koeppe, Ronald C. Petersen, P. Aisen, M. Weiner, William J. Jagust. Annals of Neurology, 2012

702 citations recorded by the source corpus.

Using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) population, we examined (1) cross‐sectional relationships between amyloid deposition, hypometabolism, and cognition, and (2) associations between amyloid and hypometabolism measurements and longitudinal cognitive measurements.

Subfields: Neurology, Physiology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/a19c29c87341aee3c1773b4210be2c935ac59c9c

Citations in the corpus

• PET Imaging of Tau Deposition in the Aging Human Brain (2016, unknown): “We also found that global Ab was related to retrospective longitudinal decline in global cognition, consistent with findings from a series of studies using CSF and PET measures of Ab in relation to cognitive performance (Fagan et al., 2007; Landau et al., 2012; Villemagne et al., 2013).”
• Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease (2017, unknown): “CSF p-tau, mean (SD), ng/L 25 (15) 36 (19) 44 (20) <.”