HIV vaccine design and the neutralizing antibody problem

By D. Burton, R. Desrosiers, R. Doms, W. Koff, P. Kwong, John P. Moore, G. Nabel, J. Sodroski, Ian A. Wilson, R. Wyatt. Nature Immunology, 2004

844 citations recorded by the source corpus.

Subfields: Immunology, Infectious Diseases, Virology

View Paper: https://www.semanticscholar.org/paper/a10ccc564e24524dba6ed417729a1ff8e31e0d9b

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In Infectious Diseases

1. Ian A. Wilson
2. Abdo A. Elfiky

Citations in the corpus

• A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies (2013, background): “A better mimic of the native, trimeric Env spike may be a superior immunogen for bNAb induction [1,5,6,7,8].”
• Reductionism and complexity in molecular biology (2004, background): “Although a re-ductionist approach to HIV-vaccine development continues to be advocated (Burton et al , 2004), there is no evidence that this will be effective.”