Polymeric Nanoparticles: Production, Characterization, Toxicology and Ecotoxicology
By A. Zielińska, F. Carreiro, A. M. Oliveira, A. Neves, B. Pires, D. Venkatesh, A. Durazzo, M. Lucarini, P. Eder, Amélia M. Silva and 2 more. Molecules, 2020
1,163 citations recorded by the source corpus.
Polymeric nanoparticles (NPs) are particles within the size range from 1 to 1000 nm and can be loaded with active compounds entrapped within or surface-adsorbed onto the polymeric core. The term “nanoparticle” stands for both nanocapsules and nanospheres, which are distinguished by the morphological structure. Polymeric NPs have shown great potential for targeted delivery of drugs for the treatment of several diseases. In this review, we discuss the most commonly used methods for the production and characterization of polymeric NPs, the association efficiency of the active compound to the polymeric core, and the in vitro release mechanisms. As the safety of nanoparticles is a high priority, we also discuss the toxicology and ecotoxicology of nanoparticles to humans and to the environment.
Subfields: Biomaterials, Electronic, Optical and Magnetic Materials, Materials Chemistry
View Paper: https://www.semanticscholar.org/paper/a0d9f3e086b292545405142f6c55d7656a12080f
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In Biomaterials
In Electronic, Optical and Magnetic Materials
In Materials Chemistry
Citations in the corpus
- A review on nanoparticles: characteristics, synthesis, applications, and challenges (2023, background): “They resemble Nano spheres or Nano capsules for the most part (Khan et al., 2019; Zielińska et al., 2020).”