Plasma brain natriuretic peptide concentration: impact of age and gender.

By M. Redfield, R. Rodeheffer, Steven Jacobsen, Douglas W. Mahoney, Kent R. Bailey, J. Burnett. Journal of the American College of Cardiology, 2002

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Systolic and diastolic heart failure in the community. (2006, neutral): “Diabetes mellitus 206 (37) 111 (36) 95 (38) .”
Progression of Left Ventricular Diastolic Dysfunction and the Risk of Heart Failure (2011, background): “Diabetes (examination 2) 17 (23) 114 (10) 2.”
N‐Terminal Pro‐Brain Natriuretic Peptide and Other Risk Markers for the Separate Prediction of Mortality and Subsequent Myocardial Infarction in Patients With Unstable Coronary Artery Disease: A Global Utilization of Strategies To Open occluded arteries (GUSTO)‐IV Substudy (2003, neutral): “Angina pectoris, % (n) 42.0 (714) 45.2 (759) 48.4 (817) 52.8 (891) 0.001 MI, % (n) 17.9 (304) 28.0 (473) 33.5 (567) 42.9 (723) 0.001 Revascularization, % (n) 11.3 (193) 16.2 (274) 17.5 (298) 15.9 (270) 0.001 Heart failure, % (n) 2.8 (47) 5.0 (85) 6.6 (112) 15.4 (259) 0.001 Stroke, % (n) 1.0 ( 17 ) 1”
State of the art: Using natriuretic peptide levels in clinical practice (2008, background): “Many people with substantial LV dysfunction do not have symptoms [95–97] but might be identified by a simple screening test such as BNP/NT-proBNP.”
Natriuretic peptides. (2007, background): “(13), which xcluded patients with “age-related” diastolic dysfunction, onetheless found an association between age and elevated evels of BNP.”