C/EBPα:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBPα homodimers or AP-1
By Alan D. Friedman, D. Cai, Dehua Wang, J. Keefer, C. Yeamans, K. Hensley. Oncogene, 2007
87 citations recorded by the source corpus.
Subfields: Molecular Biology, Virology
View Paper: https://www.semanticscholar.org/paper/a0a52899c88491da049ac756d758d1fe3e6828c3
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In Molecular Biology
Citations in the corpus
- Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities (2010, background): “In addition, C/EBP-bound regions were co-enriched for a recently described C/EBP:AP-1 composite element (Cai et al., 2008) as well as canonical PU.1 and AP-1 motifs, whereas Oct-2-bound regions in B cells were highly enriched for a PU.1 as well as a PU.1-IRF composite motif (Figure 2E).”