Effects of stress throughout the lifespan on the brain, behaviour and cognition

By Sonia J. Lupien, Bruce S. McEwen, Megan R. Gunnar, Christine Marcelle Heim. Nature Reviews Neuroscience, 2009

3,993 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Education, Pediatrics, Perinatology and Child Health

View Paper: https://www.semanticscholar.org/paper/a0113241e6bbe11348ff3e758d627be26d370b8d

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In Behavioral Neuroscience

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Citations in the corpus

RESILIENCE TRAINING THAT CAN CHANGE THE BRAIN (2018, background): “Recall that chronic stress can lead to brain cell loss in the PFC and abnormal cell growth in the amygdala, changes associated with mood and cognitive impairment (Lupien et al., 2009).”
Mindfulness-based interventions in schools—a systematic review and meta-analysis (2014, background): “Children and youth frequently experience stress in school (Currie et al., 2002; Lohaus and Ball, 2006; Card and Hodges, 2008), which has an impact on the brain structures involved in cognition and mental-health (Lupien et al., 2009).”
The Temporal Elements of Psychological Resilience: An Integrative Framework for the Study of Individuals, Families, and Communities (2015, background): “…for example atypically large amygdala volume (Tottenham et al., 2010), precocious amygdala-prefrontal connectivity (Gee et al., 2013), and rigid and inappropriate patterns of response, (e.g., either hypo- or hyperglucocorticoid response) at later developmental phases (Lupien et al., 2009).”
Regulation of the Hypothalamic‐Pituitary‐Adrenocortical Stress Response (2016, neutral): “Although not as well studied, in humans maintenance of the SHRP may also depend on parental care and social stimulation (63), suggesting that the absence of these factors may disrupt the SHRP and disrupt the normal development of the stress response (104).”
Effects of Public Green Space on Acute Psychophysiological Stress Response: A Systematic Review and Meta-Analysis of the Experimental and Quasi-Experimental Evidence (2019, background): “The phenomenon is sometimes referred to as allostatic load (McEwen, 1998) and is linked to a wide array of physical and mental health impairments, as well as physiological and emotional dysregulation (Lupien et al., 2009; Shonkoff et al., 2009).”
Some reflections on the origins of MBSR, skillful means, and the trouble with maps (2011, background): “New evidence in fact demonstrates that chronic stress exerts potentially deleterious health effects on the brain, on one’s behaviour, and on cognitive abilities across the entire lifespan, with particular windows of heightened vulnerability (Lupien et al. 2009).”
Stress signalling pathways that impair prefrontal cortex structure and function (2009, neutral): “Changes in utero and during childhood probably contribute to the susceptibility to formal mental illnesses that emerge during adolescence and adulthoo”
Psychological Stress in Childhood and Susceptibility to the Chronic Diseases of Aging: Moving Towards a Model of Behavioral and Biological Mechanisms (2011, background): “Heim et al. (2000); Luecken and Lemery (2004); Lupien et al. (2009); Meewisse et al. (2007); Miller et al. (2007); Troxel and Matthews (2004); van der Vegt et al. (2009) - Prolonged exposure to altered cortisol output, whether low or high, can facilitate inflammatory responding of macrophages.”
Mate choice for cognitive traits: a review of the evidence in nonhuman vertebrates (2011, background): “2004), and humans (reviewed in, e.g., Levitsky and Strupp 1995; Lupien et al. 2009).”