The Role of BCS (Biopharmaceutics Classification System) and BDDCS (Biopharmaceutics Drug Disposition Classification System) in Drug Development

By L. Benet. Journal of Pharmacy and Science, 2012

313 citations recorded by the source corpus.

BCS and BDDCS are complimentary, not competing, classification systems that aim to improve, simplify, and speed drug development. Although both systems are based on classifying drugs and NMEs into four categories using the same solubility criteria, they differ in the criterion for permeability and have different purposes. Here the details and applications of both systems are reviewed with particular emphasis of their role in drug development.

Subfields: Computational Theory and Mathematics, Pharmacology, Spectroscopy

View Paper: https://www.semanticscholar.org/paper/9ff8dbc453b544b8fe0649992e124ab8633cfbbd

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Citations in the corpus

• Solid Lipid Nanoparticles for Drug Delivery: Pharmacological and Biopharmaceutical Aspects (2020, background): “Proof of this is that, to date, approximately 39% of the marketed drugs (Benet, 2013) and 60% of the new chemical entities (Kovačević, 2020) belong to the biopharmaceutical categories that group low solubility drugs (i.”