Molecularly Imprinted Polymers: Present and Future Prospective
By G. Vasapollo, R. Sole, Lucia Mergola, M. R. Lazzoi, Anna Scardino, S. Scorrano, G. Mele. International Journal of Molecular Sciences, 2011
1,010 citations recorded by the source corpus.
Molecular Imprinting Technology (MIT) is a technique to design artificial receptors with a predetermined selectivity and specificity for a given analyte, which can be used as ideal materials in various application fields. Molecularly Imprinted Polymers (MIPs), the polymeric matrices obtained using the imprinting technology, are robust molecular recognition elements able to mimic natural recognition entities, such as antibodies and biological receptors, useful to separate and analyze complicated samples such as biological fluids and environmental samples. The scope of this review is to provide a general overview on MIPs field discussing first general aspects in MIP preparation and then dealing with various application aspects. This review aims to outline the molecularly imprinted process and present a summary of principal application fields of molecularly imprinted polymers, focusing on chemical sensing, separation science, drug delivery and catalysis. Some significant aspects about preparation and application of the molecular imprinting polymers with examples taken from the recent literature will be discussed. Theoretical and experimental parameters for MIPs design in terms of the interaction between template and polymer functionalities will be considered and synthesis methods for the improvement of MIP recognition properties will also be presented.
Subfields: Analytical Chemistry, Biomedical Engineering, Spectroscopy
View Paper: https://www.semanticscholar.org/paper/9f9404de6b9fcbc1fbf281adffb33e61ee85eca3
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Citations in the corpus
- Occurrence, Toxicity, and Analysis of Major Mycotoxins in Food (2017, background): “Molecular imprinting polymers: Molecular imprinting polymers (MIPs) is a synthetic technique that is designed to mimic natural recognition entities such as antibodies and biological receptors with specificities comparable to those of antibody-antigen interactions [126].”
- Oriented immobilization of proteins on solid supports for use in biosensors and biochips: a review (2015, background): “The platform offers many advantages [127]: the high selectivity and affinity for the target molecules; the higher physical robustness, strength, and resistance to elevated temperature or chemical reagents compared with bioaffinity molecules or tags; a low cost and long storage life of the imprinted ”