Some Like It Hot, But Not the First Biomolecules

By J. Bada, A. Lazcano. Science, 2002

207 citations recorded by the source corpus.

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On the origins of cells: a hypothesis for the evolutionary transitions from abiotic geochemistry to chemoautotrophic prokaryotes, and from prokaryotes to nucleated cells. (2003, background): “Owing to the very poor stability of critical building blocks of life such as RNA, temperatures closer to 50 °C seem more conducive to the assembly and sustained stability of early organic molecules and self-reproducing systems (Moulton et al. 2000; Bada & Lazcano 2002).”
A cold and wet Mars (2010, background): “, 2005) and cold environment (Bada and Lazcano, 2002; Vlassov et al., 2004, 2005; Trinks et al., 2005) were likely prevalent.”
On the origin of biochemistry at an alkaline hydrothermal vent (2007, background): “But, many scientists still prefer the idea of a prebiotic soup (Bada & Lazcano 2002) in which the first organisms wouldhave survived fromoxidationof the soup’s reduced carbon compounds (de Duve 1991).”
Origins of building blocks of life: A review (2017, background): “and/or on mineral surfaces rather than in bulk oceanic water (Bada and Lazcano, 2002).”