Heterosynaptic depression: a postsynaptic correlate of long-term potentiation

By Gary Lynch, T. Dunwiddie, Valentin Gribkoff. 1977

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Citations in the corpus

Neuromodulated Spike-Timing-Dependent Plasticity, and Theory of Three-Factor Learning Rules (2016, background): “In the absence of extracellular Mg2+, LTP is observed at normal dopamine levels (instead of LTD), but LTP induction is not possible if D1/D5 dopamine receptors are blocked (Kerr and Wickens, 2001).”
Memristor-based neural networks (2013, methodology): “This was investigated using a tetanized pathway and a control path in 17 matched-pair experiments by Lynch et al [50].”
Plasticity of Cortical Excitatory-Inhibitory Balance (2015, background): “After LTP induction at one set of excitatory inputs, heterosynaptic LTD can be observed within several minutes at other excitatory synapses onto the same cell (Christie et al. 1994, Lynch et al. 1977).”
A synaptic organizing principle for cortical neuronal groups (2011, background): “Although Hebb (1) had suggested a mechanism for passive weakening of unused synaptic connections, these objections suggested the need for an active depressive mechanism (16, 17, 23), inspiring the discoveries of long-term depression (LTD) (24) and bidirectional and spike timing-dependent plasticity ”
Heterosynaptic structural plasticity on local dendritic segments of hippocampal CA1 neurons (2014, background): “In this study, we hypothesized that competitive interactions with neighboring synapses may also play a major role in the structural plasticity associated with synaptic weakening, as it is well-established that stimuli that induce long-term potentiation (LTP) of synaptic strength in one population of”
Cortical plasticity: from synapses to maps. (1998, background): “Heterosynaptic LTD has been reported in the CA1 region of the hippocampus (Lynch et al 1977, Pockett et al 1990, Cummings et al 1996, Scanziani et al 1996), in CA3 (Bradler & Barrionuevo 1990), and in the neocortex (Hirsch et al P1: SKH/dat P2: MBL/vks QC: MBL December 21, 1997 13:17 Annual Reviews…”
Heterosynaptic Plasticity Prevents Runaway Synaptic Dynamics (2013, background): “Using a conductance-based model, we show that STDP operating alone on the input synapses to the cell driven by correlated spike trains often leads to unstable synaptic weight dynamics: a slight bias of STDP rules toward LTP or LTD triggers runaway dynamics with synaptic weights evolving toward the m”
Synaptic modification by correlated activity: Hebb's postulate revisited. (2001, background): “Heterosynaptic LTD Early studies of LTP in the CA1 region of hippocampus have shown a depression of unstimulated commissural-CA1 synapses following LTP-inducing tetanic stimulation of Schaffer collaterals (Lynch et al 1977, Dunwiddie & Lynch 1978).”