The PDGF family: four gene products form five dimeric isoforms.
By L. Fredriksson, Hong Li, U. Eriksson. Cytokine & growth factor reviews, 2004
864 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/9f42bc6fc02bb464fa2a44aa2c6a9e63f2e4b4fe
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In Cancer Research
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Citations in the corpus
- Role of platelet-derived growth factors in physiology and medicine. (2008, neutral): “Plasmin can cleave and activate also PDGF-D, but tPA cannot (Fredriksson et al. 2004b).”
- Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex (2010, background): “Although functional evidence only exists for the homodimeric PDGF-A/PDGFRα, PDGF-C/PDGFRα, and PDGF-B/PDGFRβ complexes, biochemical data support additional homodimeric and heterodimeric combinations (5).”
- PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. (2009, background): “Platelet-derived growth factor C (PDGF-C) (Li et al., 2000) is a member of the PDGF family (Aase et al., 2002; Andrae et al., 2008; Ding et al., 2000; Fredriksson et al., 2004).”