Biosensors and Bio-Bar Code Assays Based on Biofunctionalized Magnetic Microbeads
By N. Jaffrezic‐Renault, C. Martelet, Y. Chevolot, J. Cloarec. Italian National Conference on Sensors, 2007
119 citations recorded by the source corpus.
This review paper reports the applications of magnetic microbeads in biosensors and bio-bar code assays. Affinity biosensors are presented through different types of transducing systems: electrochemical, piezo electric or magnetic ones, applied to immunodetection and genodetection. Enzymatic biosensors are based on biofunctionalization through magnetic microbeads of a transducer, more often amperometric, potentiometric or conductimetric. The bio-bar code assays relie on a sandwich structure based on specific biological interaction of a magnetic microbead and a nanoparticle with a defined biological molecule. The magnetic particle allows the separation of the reacted target molecules from unreacted ones. The nanoparticles aim at the amplification and the detection of the target molecule. The bio-bar code assays allow the detection at very low concentration of biological molecules, similar to PCR sensitivity.
Subfields: Biomedical Engineering, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/9f017ae8040c686a56739d19fb97a36a0024dc73
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Citations in the corpus
- Exploiting generic platform technologies for the detection and identification of plant pathogens (2008, background): “Such methods also have the potential to be combined with novel detection strategies such as the use of functionalised gold nanoparticles (Tan et al. 2005), bioluminescence (Gandelman et al. 2006), or biosensors ( Jaffrezic-Renault et al. 2007 ), which could be less costly than the fluorescent detect”
- Label free polyaniline based impedimetric biosensor for detection of E. coli O157:H7 Bacteria (2012, unknown): “[2–5].”
- Iron and iron-oxide magnetic nanoparticles as signal-amplification elements in electrochemical biosensing (2015, background): “Ironbased MNPs are particularly efficient in detecting analytes in complex samplematrices, whichmay exhibit either poormass transport to the biosensor or physical blockage of the biosensor surface by non-specific adsorption [16].”
- Electrochemical sensors based on metal and semiconductor nanoparticles (2009, background): “These magnetic particles are especially designed for labeling cells [245].”