Neonicotinoids: insecticides acting on insect nicotinic acetylcholine receptors.

By Kazuhiko Matsuda, S. Buckingham, Daniel A. Kleier, J. Rauh, M. Grauso, D. Sattelle. TIPS - Trends in Pharmacological Sciences, 2001

892 citations recorded by the source corpus.

Subfields: Ecology, Evolution, Behavior and Systematics, Insect Science

View Paper: https://www.semanticscholar.org/paper/9eda5ebc818e29e77f2b559f71cdb1c7b928f287

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In Ecology, Evolution, Behavior and Systematics

1. S. Potts
2. Dave Goulson
3. N. E. Raine
4. Richard J. Gill
5. Josef Settele
6. P. Neumann
7. C. Morrissey
8. P. Mineau

In Insect Science

1. N. E. Raine
2. Richard J. Gill
3. S. Potts
4. Dave Goulson
5. D. McCullough
6. P. Neumann
7. C. Morrissey
8. P. Mineau

Citations in the corpus

• Sublethal doses of imidacloprid decreased size of hypopharyngeal glands and respiratory rhythm of honeybees in vivo (2013, positive): “These insecticides act on the insect central nervous system (CNS), as agonists of the postsynaptic nicotinic acetylcholine receptor (nAChRs) (Matsuda et al. 2001; Brown et al. 2006).”
• Distribution of trunk-injected 14C-imidacloprid in ash trees and effects on emerald ash borer (Coleoptera: Buprestidae) adults (2009, background): “This compound acts at the nicotinic acetylcholine receptors (nAChRs) in the insect nervous system (Schroeder and Flattum, 1984; Bai et al., 1991; Matsuda et al., 2001).”
• Sublethal neonicotinoid insecticide exposure reduces solitary bee reproductive success (2014, background): “Considering the general mode of neurotoxic action of neonicotinoids in insects (Matsuda et al., 2001; Desneux et al., 2007), toxicological effects resulting in behavioural, cognitive or locomotive abnormalities could result in the devastating fitness response reported in the present study in solitar”
• Environmental fate and exposure; neonicotinoids and fipronil (2014, background): “class of insecticides (Matsuda et al. 2005) that are utilized in”
• Chronic impairment of bumblebee natural foraging behaviour induced by sublethal pesticide exposure (2014, background): “Imidacloprid is known to act as a neuronal partial agonist (Deglise, Gr€unewald & Gauthier 2002) that can acutely increase neuronal activity (Matsuda et al. 2001), which may explain why we observe increased forager activity (i.e. hyperactiv- ity: Suchail, Guez & Belzunces 2001).”
• Neonicotinoids in bees: a review on concentrations, side-effects and risk assessment (2012, background): “…insecticides, which include imidacloprid, acetamiprid, clothianidin, thiamethoxam, thiacloprid, dinotefuran and nitenpyram, are an important group of neurotoxins specifically acting as antagonists of the insect nicotinic acetylcholine receptors (nAChR) (Matsuda et al. 2001; Elbert et al. 2008).”
• Imidacloprid impairs memory and brain metabolism in the honeybee (Apis mellifera L.) (2004, background): “001 had a high agonistic affinity with nicotinic acetylcholine receptors (nAChR)(1) of insects [2].”
• Systemic insecticides (neonicotinoids and fipronil): trends, uses, mode of action and metabolites (2014, background): “Differences in properties and structure of the subunits between insects and mammalian nAChRs explain in part the high selectivity of neonicotinoids to arthropods and the supposed relatively low toxicity to vertebrates (Nauen et al. 1999; Lansdell and Millar 2000; Matsuda et al. 2001; Tomizawa and Ca”
• Biotic and Abiotic Factors Associated with Colonies Mortalities of Managed Honey Bee (Apis mellifera) (2019, background): “Neonicotinoids bind to the nicotinic receptors located in the postsynaptic membrane of neurons to cause their activation because they are agonists of the receptor [90,91].”