The DNA methylation landscape of human early embryos

By Hongshan Guo, P. Zhu, Liying Yan, Rong Li, Boqiang Hu, Y. Lian, Jie Yan, Xiulian Ren, Shengli Lin, Junsheng Li and 15 more. Nature, 2014

861 citations recorded by the source corpus.

Subfields: Molecular Biology, Pediatrics, Perinatology and Child Health

View Paper: https://www.semanticscholar.org/paper/9e36c98c6d894fb17039cf9c915e81e38fb18c06

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Jennifer Nichols
2. Wolf Reik
3. Austin G Smith
4. Nir Yosef
5. G. Guo
6. Aviv Regev
7. Fátima Santos
8. Felix Krueger

In Pediatrics, Perinatology and Child Health

1. Wolf Reik
2. Fátima Santos

Citations in the corpus

• Revealing the vectors of cellular identity with single-cell genomics (2016, methodology): “…on RNA and protein, recent progress in epigenome analysis 192 has included assays for single-cell ChIP-seq (Drop-ChIP 26 ), single-cell ATAC-seq 27,28 , single-cell Hi-C 29 (a genome-wide derivative of the chromosome conformation capture (3C) technique), and single-cell DNA methylation 22–25 .”
• A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development (2015, methodology): “Due to low coverage, ICM only has 42% of common tiles fulfilling the above criteria.”
• Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human (2014, background): “The global reduction in DNA methylation in reset cells is similar in magnitude to hypomethylation in mouse ground-state ESC and in line with the demethylated status reported for the human inner cell mass (ICM) (Guo et al., 2014; Smith et al., 2014).”