Multi-Contrast Human Neonatal Brain Atlas: Application to Normal Neonate Development Analysis
By K. Oishi, Susumu Mori, P. Donohue, T. Ernst, L. Anderson, S. Buchthal, A. Faria, Hangyi Jiang, Xin Li, Michael I. Miller and 2 more. NeuroImage, 2011
319 citations recorded by the source corpus.
MRI is a sensitive method for detecting subtle anatomic abnormalities in the neonatal brain. To optimize the usefulness for neonatal and pediatric care, systematic research, based on quantitative image analysis and functional correlation, is required. Normalization-based image analysis is one of the most effective methods for image quantification and statistical comparison. However, the application of this methodology to neonatal brain MRI scans is rare. Some of the difficulties are the rapid changes in T1 and T2 contrasts and the lack of contrast between brain structures, which prohibits accurate cross-subject image registration. Diffusion tensor imaging (DTI), which provides rich and quantitative anatomical contrast in neonate brains, is an ideal technology for normalization–based neonatal brain analysis. In this paper, we report the development of neonatal brain atlases with detailed anatomic information derived from DTI and co-registered anatomical MRI. Combined with a diffeomorphic transformation, we were able to normalize neonatal brain images to the atlas space and three-dimensionally parcellate images into 122 regions. The accuracy of the normalization was comparable to the reliability of human raters. This method was then applied to babies of 37 to 53 post-conceptional weeks to characterize developmental changes of the white matter, which indicated a posterior-to-anterior and a central-to-peripheral direction of maturation. We expect that future applications of this atlas will include investigations of the effect of prenatal events and the effects of preterm birth or low birth weights, as well as clinical applications, such as determining imaging biomarkers for various neurological disorders.
Subfields: Pediatrics, Perinatology and Child Health, Radiology, Nuclear Medicine and Imaging
View Paper: https://www.semanticscholar.org/paper/9e2e8106ef73a311ade7982a7062932490c1834a
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In Pediatrics, Perinatology and Child Health
In Radiology, Nuclear Medicine and Imaging
Citations in the corpus
- A review on automatic fetal and neonatal brain MRI segmentation (2017, unknown): “Gousias et al. (2012)2 in con- 8 M AN US CR IP T AC CE PT ED Templates Structures Time-points Subjects Single-subject atlases Neonatal Oishi et al. (2011)1 T1,T2,FA,MD 122 regions 1 term 1 Gousias et al. (2012)2 T1,T2 50 regions 20 term 20 de Macedo Rodrigues et al. (2015) T1 32 regions 23 at 0,1,2 ”
- The early development of brain white matter: a review of imaging studies in fetuses, newborns and infants. (2014, background): “The interest of DTI studies rests in the quantification of differences across WM bundles, detailing a progression of maturation from a central-to-peripheral and a posterior-to-anterior direction (Oishi et al., 2011).”