Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
By C. Amos, Xifeng Wu, P. Broderick, I. Gorlov, J. Gu, T. Eisen, Q. Dong, Qing Zhang, X. Gu, J. Vijayakrishnan and 10 more. Nature Genetics, 2008
1,287 citations recorded by the source corpus.
View Paper: https://www.semanticscholar.org/paper/9d7d1c05cafb79b527fa0c1eaa45efdb9d23002f
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Citations in the corpus
- Learning your identity and disease from research papers: information leaks in genome wide association study (2009, background): “With the maturity of genotype phasing techniques [57, 55, 19, 14, 25, 28], genome research today is increasingly based upon haplotypes, which offer more accurate descripions of LD and therefore are more useful to the research.”
- A SNP in a let-7 microRNA complementary site in the KRAS 3′UTR Increases Non-Small Cell Lung Cancer Risk (2008, background): “The mechanism of lung cancer predisposition caused by these SNPs is controversial but is hypothesized to be through affects on a nicotine receptor (35, 36 ).”
- Non-small cell lung cancer: current treatment and future advances. (2016, background): “There are also reports of a marker on chromosome 15 associated with lung cancer, which was explored in three independent genetic studies (28-30).”
- Genome-wide association studies: what do they teach us about asthma and chronic obstructive pulmonary disease? (2009, background): “Since the first GWA study on lung cancer by Hung and colleagues identified this locus on the nicotinic acetylcholine receptor subunits (CHRNA5/CHRNA3, on chromosome 15q25), there has been debate on whether this locus was indeed a true underlying genetic cause of lung cancer or merely associated with”
- Detection of sharing by descent, long-range phasing and haplotype imputation (2008, background): “Here we focus on a region around the nicotinic acetylcholine receptor gene cluster ( CHRNA5 , CHRNA3 and CHRNB4 ) on 15q25 where variants, including allele T of SNP rs1051730, were recently shown to associate with smoking behavior, lung cancer and peripheral arterial diseas”
- A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci (2009, background): “Another lung cancer report by Amos and colleagues [12] did show weak evidence for association with smoking behavior, while a further report by Thorgeirsson and colleagues[14] showed very strong association with smoking behavior.”