Biomechanical Properties of In Vivo Human Skin From Dynamic Optical Coherence Elastography

By Xing Liang, S. Boppart. IEEE Transactions on Biomedical Engineering, 2009

442 citations recorded by the source corpus.

Dynamic optical coherence elastography is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young's moduli are measured on human skin from different sites, orientations, and frequencies. Skin thicknesses, including measurements from different layers, are also measured simultaneously. Experimental results show significant differences among measurements from different skin sites, between directions parallel and orthogonal to Langer's lines, and under different skin hydration states. Results also suggest surface waves with different driving frequencies represent skin biomechanical properties from different layers in depth. With features such as micrometer-scale resolution, noninvasive imaging, and real-time processing from the optical coherence tomography technology, this optical measurement technique has great potential for measuring skin biomechanical properties in dermatology.

Subfields: Biomedical Engineering, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/9ce7c53b05720e60c69ed61f35bae4b7385bcf91

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In Biomedical Engineering

In Radiology, Nuclear Medicine and Imaging

Citations in the corpus

A Soft, Wearable Microfluidic Device for the Capture, Storage, and Colorimetric Sensing of Sweat (2016, unknown): “16 MPa, comparable to human skin and previously reported epidermal devices (37, 38).”
Ultra-stretchable and skin-mountable strain sensors using carbon nanotubes–Ecoflex nanocomposites (2015, background): “5 MPa) than that of human skin (25–220 kPa), and this discrepancy becomes larger when PDMS is mixed with CNTs [1, 4, 16, 47–49].”
Characterization of the anisotropic mechanical properties of excised human skin. (2013, background): “More recent work conducted using optical coherence elastography in-vivo, indicates a large difference between the Young moduli of skin along directions parallel and orthogonal to the Langer lines (Liang and Boppart, 2010).”
Lab-on-Skin: A Review of Flexible and Stretchable Electronics for Wearable Health Monitoring. (2017, background): “16,20,24,26,29-30,48,89,116 Properties of human skin are listed for comparison.(30,50)”
A Review of Optical Coherence Elastography: Fundamentals, Techniques and Prospects (2014, methodology): “Contact methods include a metal rod or piezoelectric transducer in direct contact with the sample [23], [48], [50], [83], [100], as shown in Fig.”