Regulation of phosphoinositide-specific phospholipase C.

By S. Rhee. Annual Review of Biochemistry, 2001

1,679 citations recorded by the source corpus.

Subfields: Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/9b0dee667e68e59f103b628cec55d74b4a6c9df7

How researchers see this paper

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In Molecular Biology

1. D. Murray
2. S. McLaughlin
3. Simon Cook
4. H. Llewelyn Roderick
5. Y. Bae
6. S. Rhee

In Surgery

1. D. Murray
2. S. McLaughlin
3. H. Llewelyn Roderick
4. Simon Cook

Citations in the corpus

• Distinct coincidence detectors govern the corticostriatal spike timing‐dependent plasticity (2010, background): “…a coincidence detector involve elevation of calcium concentration, which is needed for its catalytic function, and its concomitant activation by Gq/11-coupled receptors, including group-I mGluRs, M1/M3 muscarinic and 5-HT2 serotoninergic receptors (5-HT2Rs) (Rebecchi & Pentyala, 2000; Rhee, 2001).”
• Mechanism of B-Cell Receptor-Induced Phosphorylation and Activation of Phospholipase C-γ2 (2004, background): “We have now confirmed that these three PTKs are necessary for normal induction of PLC- 2 phosphorylation by BCR stimulation.”
• Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival (2008, background): “The Ca 2+ toolkit is extensive and includes environmental sensors (for example, plasma membrane receptors that detect changes in the level of circulating hormones); signal transducers (such as G proteins and phospholipase C isoforms (PLCs”
• AN ew Mode of Ca 2 Signaling by G Protein-Coupled Receptors: Gating of IP 3 Receptor Ca 2 Release Channels by G (2003, background): “1 M bombesin (BS), 2 M ionomycin ated by G [9].”
• Recruitment and activation of PLCγ1 in T cells: a new insight into old domains (2006, background): “includes two SH2 domains followed by a single Src-homology 3 (SH3) domain (Katan, 1998; Rhee, 2001).”
• Plasma membrane phosphoinositide organization by protein electrostatics (2005, background): “Well-characterized phosphoinositide-specific phospholipase Cs (PLCs) hydrolyse PIP 2 into these second messenger”