Cytochrome 2C19*17 Allelic Variant, Platelet Aggregation, Bleeding Events, and Stent Thrombosis in Clopidogrel-Treated Patients With Coronary Stent Placement

By D. Sibbing, W. Koch, D. Gebhard, T. Schuster, S. Braun, Julia Stegherr, T. Morath, A. Schömig, N. von Beckerath, A. Kastrati. Circulation, 2010

614 citations recorded by the source corpus.

Subfields: Biochemistry, Cardiology and Cardiovascular Medicine, Hematology

View Paper: https://www.semanticscholar.org/paper/9b03835a4e52d1a8782860a633805dc4c04ad9c7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. M. Schwab
2. Ulrich M. Zanger

Citations in the corpus

• Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors (2015, background): “The currently available evidence indicates that the CYP2C19*17 increased function allele is unable to completely compensate for the no function CYP2C19*2 allele.(36) See Supplemental Materials for a more comprehensive list of pre-”
• Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation. (2013, background): “, 2008) while another study reported increased risk of bleeding events (Sibbing et al., 2010).”