Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice
By M. Mall, B. Grubb, J. Harkema, W. O’Neal, R. Boucher. Nature Medicine, 2004
953 citations recorded by the source corpus.
Subfields: Physiology, Pulmonary and Respiratory Medicine
View Paper: https://www.semanticscholar.org/paper/9ad9beb0e540df9db3d12be137c41952a5425417
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In Physiology
In Pulmonary and Respiratory Medicine
Citations in the corpus
- Consensus on the use and interpretation of cystic fibrosis mutation analysis in clinical practice. (2008, background): “Over expression of SCNN1B results in increased airway epithelial sodium absorption and CF-like lung disease in mice [72].”
- Respiratory tract mucin genes and mucin glycoproteins in health and disease. (2006, background): “Similar behavior, as well as increased amounts of mucus and altered mucus transport and mucus adhesion to airway surfaces, is observed in vivo in mice that overexpress the -subunit of the epithelial sodium channel, ENaC (174).”