Review on Natural Coumarin Lead Compounds for Their Pharmacological Activity

By Katharigatta N. Venugopala, V. Rashmi, B. Odhav. BioMed Research International, 2013

842 citations recorded by the source corpus.

Coumarin (2H-1-benzopyran-2-one) is a plant-derived natural product known for its pharmacological properties such as anti-inflammatory, anticoagulant, antibacterial, antifungal, antiviral, anticancer, antihypertensive, antitubercular, anticonvulsant, antiadipogenic, antihyperglycemic, antioxidant, and neuroprotective properties. Dietary exposure to benzopyrones is significant as these compounds are found in vegetables, fruits, seeds, nuts, coffee, tea, and wine. In view of the established low toxicity, relative cheapness, presence in the diet, and occurrence in various herbal remedies of coumarins, it appears prudent to evaluate their properties and applications further.

Subfields: Biochemistry, Endocrinology, Diabetes and Metabolism, Plant Science

View Paper: https://www.semanticscholar.org/paper/9ad2483d36e357379c0c9a5362fff720ff0ca53c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. Yuxing Deng
2. Shanfa Lu

In Plant Science

1. Yuxing Deng
2. S. Asaf
3. Shanfa Lu

Citations in the corpus

• Plant Secondary Metabolite Biosynthesis and Transcriptional Regulation in Response to Biotic and Abiotic Stress Conditions (2021, background): “They were initially reported in the tonka bean (Dipteryx odorata) and subsequently reported in around 150 different species from 30 families [11].”
• Biosynthesis and Regulation of Phenylpropanoids in Plants (2017, background): “In addition, coumarins have broad pharmacological prospective and have aroused a wide concern in medicine development (Ojala et al., 2000; Venugopala et al., 2013).”