Cancer Progress and Priorities: Lung Cancer

By Matthew B. Schabath, M. Cote. Cancer Epidemiology, Biomarkers and Prevention, 2019

882 citations recorded by the source corpus.

Background In the United States, lung cancer is the second most common diagnosed cancer and the leading cause of cancer-related death. Though tobacco smoking is the major risk factor accounting for 80 to 90% of all lung cancer diagnoses, there are numerous other risk factors that have been identified as casually associated with lung cancer etiology. However, there are few causally-linked risk factors for lung cancer diagnosed among never smokers which, if considered a unique reportable category, is the 11th most common cancer and the 7th leading cause of cancer-related death. Lung cancer survival has only marginally improved over the last several decades, but the availability of screening and early detection by low-dose computer tomography and advances in targeted treatments and immunotherapy will likely decrease mortality rates and improve patient survival outcomes in the near future.

Subfields: Oncology, Pulmonary and Respiratory Medicine, Surgery

View Paper: https://www.semanticscholar.org/paper/9accd5d25987c87ec19e9a9f2f2836041e4b8101

Citations in the corpus

• Traj-CoA: Patient Trajectory Modeling via Chain-of-Agents for Lung Cancer Risk Prediction (2025, unknown): “These are either widely recognized by clinical practice and screening guidelines for assessing lung cancer risk [54, 55], or consistent with existing evidence [56, 57, 58].”