Morphine, gabapentin, or their combination for neuropathic pain.

By S. Tesfaye, D. Selvarajah. New England Journal of Medicine, 2005

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Algorithm for neuropathic pain treatment: An evidence based proposal (2005, neutral): “…0/50 0/50 ns 5/50 5/50 ns Gabapentin, 900–2400 mg bfSerpell, 2002, 5 Parallel, 307 GabOpla 32/153 21/152 ns 24/153 25/152 ns Gabapentin, 3200 mg Gilron et al., 2005, 5 Cross-over, 41 GabZpla 27/44 13/42 3.3 (2.0–9.7) 4/48 1/44 ns Opioids Painful polyneuropathy Tramadol, 200–400 mg aHarati…”
Recommendations for the management of herpes zoster. (2007, background): “Nevertheless, a substantial percentage of patients are often refractory to these treatments used alone or in combination [111] and require treatment in settings specializing in pain management.”
Diabetic Neuropathy: A Position Statement by the American Diabetes Association (2016, background): “Some studies report an improvement in quality of life in people with painful DSPN treated with duloxetine (100), pregabalin (141), and gabapentin (106,142).”
EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision (2010, background): “However, the most consistent effects were observed with pregabalin and gabapentin on sleep quality [40,98], and poor results were reported with pregabalin on QoL or mood in 6 trials.”
Systematic Review: Opioid Treatment for Chronic Back Pain: Prevalence, Efficacy, and Association with Addiction (2007, background): “In addition, trials should be of a longer duration to reflect the way in which opioids are used clinically (56).”