Comprehensive Evaluation of Tamoxifen Sequential Biotransformation by the Human Cytochrome P450 System in Vitro: Prominent Roles for CYP3A and CYP2D6

By Z. Desta, B. Ward, N. Soukhova, D. Flockhart. Journal of Pharmacology and Experimental Therapeutics, 2004

652 citations recorded by the source corpus.

Subfields: Genetics, Pharmacology

View Paper: https://www.semanticscholar.org/paper/9a61f56e970498da43d24ffa3fcead878971dfe5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Shufeng Zhou

In Pharmacology

1. Shufeng Zhou
2. Jun-Ping Liu
3. B. Chowbay

Citations in the corpus

• Polymorphism of human cytochrome P450 enzymes and its clinical impact (2009, background): “There are two major metabolic routes for fluoxetine: N-demethylation to norfluoxetine (desmethylfluoxetine) and O-dealkylation to p-trifluoromethylphenol (Figure 69).”