Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission

By J. Lighter, M. Phillips, S. Hochman, Stephanie A. Sterling, Diane S. Johnson, F. François, A. Stachel. Clinical Infectious Diseases, 2020

1,108 citations recorded by the source corpus.

Abstract

Subfields: Infectious Diseases, Neurology, Oncology

View Paper: https://www.semanticscholar.org/paper/9a09bb6105377c2c8ce066bfed3107ace676daed

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Infectious Diseases

1. Miguel A. Hern'an
2. M. J. van der Laan

In Oncology

1. Matthew D. Hall
2. Barry M. Popkin

Citations in the corpus

• Prevalence and Impact of Myocardial Injury in Patients Hospitalized With COVID-19 Infection (2020, positive): “Interestingly, higher BMI was associated with increased mortality in the setting of COVID-19 among our cohort, consistent with a prior report (30).”
• Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19 (2020, background): “19 Other symptoms, including neurologic symptoms and coagulopathies, have also been reported in a portion of infected individuals. 20−24 Similar to other coronaviruses, SARS-CoV-2 primarily infects the respiratory and gastrointestinal tract, with a cell tropism of nasal epithelial cells, pneumocytes”
• Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US. (2020, background): “Hospital length of stay, median (IQR), d NA 16 (11-22) NA”
• Individuals with obesity and COVID‐19: A global perspective on the epidemiology and biological relationships (2020, background): “Emerging literature suggests that adults with obesity under the age of 60 are more likely to be hospitalized.(1) The COVID-19 pandemic has occurred at a time when the prevalence of individuals with overweight/obesity is increasing in vir-”
• OpenSAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients. (2020, background): “63)(6); obesity was also reported as a risk factor for treatment escalation in smaller studies in France and New York.(7,8) .”
• COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection (2021, background): “Approximately 50% of hospitalized COVID-19 patients have pre-existing medical conditions, including hypertension [78], diabetes mellitus (DM) [79, 80], cardiovascular disease [19, 81, 82], cerebrovascular disease [82], obesity [19, 83, 84], chronic kidney disease [19, 85], smoking [86, 87], and chro”