Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly.
By Florian Zink, S. Stacey, G. Norddahl, M. Frigge, O. Magnusson, I. Jónsdóttir, Thorgeir E. Thorgeirsson, A. Sigurdsson, S. A. Gudjonsson, J. Gudmundsson and 12 more. Blood, 2017
713 citations recorded by the source corpus.
Subfields: Cancer Research, Genetics, Hematology
View Paper: https://www.semanticscholar.org/paper/99f6d56648123e04c14d6b20f666d989dd70267a
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Citations in the corpus
- Clonal hematopoiesis in human aging and disease (2019, positive): “Several studies have found that CHIP is associated with a 30 to 40% increased mortality risk (28, 29, 38).”
- Tet2-mediated Clonal Hematopoiesis Accelerates Heart Failure through a Mechanism Involving the IL-1β/NLRP3 Inflammasome (2018, background): “Recent longitudinal studies have reported that detectable clonal hematopoiesis in non-symptomatic individuals is associated with all-cause mortality (6,7,9).”